Xigduo XR a Prescription Medication Used to Control Blood Sugar Levels



Xigduo XR

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Dapagliflozin and metformin are oral diabetes medicines that help control blood sugar levels.

Dapagliflozin and metformin is a combination medicine used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.This medicine is not for treating type 1 diabetes.

Dapagliflozin and metformin may also be used for purposes not listed in this medication guide.

You should not use this medicine if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment).

You may developlactic acidosis,a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.

You should not use this medicine if you are allergic to dapagliflozin (Farxiga) or metformin, or if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment with insulin).

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you will need to temporarily stop taking this medicine.

Tell your doctor if you have ever had:

  • liver or kidney disease;
  • low blood pressure;
  • a bladder infection or urination problems;
  • bladder cancer;
  • heart problems;
  • problems with your pancreas, including surgery; or
  • if you are on a low salt diet.

You may developlactic acidosis,a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.

Tell your doctor right away if you become pregnant.Dapagliflozin may harm the unborn baby if you take this medicine during your second or third trimester.

Metformin may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.

You should not breast-feed while using this medicine.

Dapagliflozin and metformin is not approved for use by anyone younger than 18 years old.

Xigduo Xr Side Effects

Get emergency medical help if you havesigns of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Mild symptoms of lactic acidosis may worsen over time, and this condition can be fatal. Get emergency medical help if you have: unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired.

Call your doctor at once if you have:

  • little or no urination;
  • dehydration symptoms--dizziness, weakness, feeling light-headed (like you might pass out);
  • ketoacidosis (too much acid in the blood)--nausea, vomiting, stomach pain, confusion, unusual drowsiness, or trouble breathing;
  • signs of a bladder infection--pain or burning when you urinate, increased urination, blood in your urine, fever, pain in your pelvis or back; or
  • signs of a genital infection (penis or vagina)--pain, burning, itching, rash, redness, odor, or discharge.

Some people taking dapagliflozin have had bladder cancer, but it is not clear if this medicine was the actual cause.

Side effects may be more likely to occur in older adults.

Common side effects may include:

  • genital infections;
  • headache;
  • nausea, vomiting, diarrhea; or
  • runny or stuffy nose, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Xigduo Xr Interactions

Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Tell your doctor about all your other medicines, especially:

  • digoxin (digitalis, Lanoxin);
  • a diuretic or "water pill";
  • insulin or other oral diabetes medications;
  • rifampin;
  • ritonavir;
  • NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others; or
  • seizure medicine--phenobarbital, phenytoin.

This list is not complete. Other drugs may affect dapagliflozin and metformin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Xigduo Xr Dosage

Your doctor may perform kidney function tests before you start taking dapagliflozin and metformin.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take with food to prevent an upset stomach.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Low blood sugar(hypoglycemia)can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, irritability, dizziness, nausea, and feeling shaky. To quickly treat low blood sugar, always keep a fast-acting source of sugar with you such as fruit juice, hard candy, crackers, raisins, or non-diet soda.

Your doctor can prescribe a glucagon emergency injection kit to use in case you have severe hypoglycemia and cannot eat or drink. Be sure your family and close friends know how to give you this injection in an emergency.

Also watch for signs of high blood sugar(hyperglycemia)such as increased thirst or urination, blurred vision, headache, and tiredness.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals.Ask your doctor before changing your dose or medication schedule.

Your doctor may have you take extra vitamin B12 while you are taking dapagliflozin and metformin. Take only the amount of vitamin B12 that your doctor has prescribed.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medicine, which can lead to severely low blood pressure or a serious electrolyte imbalance.

If you need surgery or medical tests, tell any doctor who treats you that you are using dapagliflozin and metformin.

This medicine is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Your doctor may have you take extra vitamin B12 while you are taking dapagliflozin and metformin. Take only the amount of vitamin B12 that your doctor has prescribed.

Store at room temperature, away from moisture and heat.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have severely low blood sugar (extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, or seizure).

Take the medicine (with food) as soon as you can, but skip the missed dose if it is almost time for your next dose.Do nottake two doses at one time.

Copyright 1996-2019 Cerner Multum, Inc.






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Date: 06.12.2018, 19:04 / Views: 63252